Statistics of Nascent and Mature RNA Fluctuations in a Stochastic Model of Transcriptional Initiation, Elongation, Pausing, and Termination

. 2020 Dec 22;83(1):3. doi: 10.1007/s11538-020-00827-7

Reaction	Rate function $f_{j}$
$G_{on} \overset{s_{b}}{⟶} G_{off}$	$f_{1} = s_{b} ⟨ n_{0} ⟩$
$G_{off} \overset{s_{u}}{⟶} G_{on}$	$f_{2} = s_{u} (1 - ⟨ n_{0} ⟩)$
$G_{on} \overset{r}{⟶} G_{on} + P_{1}$	$f_{3} = r ⟨ n_{0} ⟩$
$P_{i} \overset{k}{⟶} P_{i + 1}$ , $i \in {1, \dots, L - 1}$	$f_{i + 3} = k ⟨ n_{i} ⟩$
$P_{L} \overset{k}{⟶} M$	$f_{L + 3} = k ⟨ n_{L} ⟩$
$P_{i} \overset{d}{⟶} \emptyset$ , $i \in {1, \dots, L}$	$f_{i + L + 3} = d ⟨ n_{i} ⟩$
$M \overset{d_{m}}{⟶} \emptyset$	$f_{2 L + 4} = d_{m} ⟨ n ⟩$