Table 2:
Association between Surgical Anesthesia and Volumetric and Cortical Surface Measures at TEA
| No Surgery | Surgery | No Surgery | Surgery | |||||
|---|---|---|---|---|---|---|---|---|
| Tissue Volumes (cm3) | Absolute Volumes | p1 | p2 | Relative Volumes (%) | p1 | p3 | ||
| White Matter | 133.3 (1.8) | 126.3 (2.0) | 0.056 | 0.19 | 48.1 (3.2) | 45.6 (8.0) | 0.001 | 0.007 |
| Cortical Gray Matter | 102.8 (1.8) | 112.7 (2.1) | 0.003 | 0.478 | 37.4 (3.1) | 40.5 (4.0) | 0.001 | 0.007 |
| DNGM | 22.9 (0.3) | 22.0 (0.4) | 0.14 | 0.056 | 8.3 (.6) | 8.0 (.7) | 0.153 | .081 |
| Cerebellum | 16.9 (0.4) | 16.6 (0.5) | 0.125 | 0.156 | 6.3 (.7) | 5.9 (.8) | 0.029 | 0.626 |
| Total Tissue | 279.9 (5.1) | 270.1 (6.1) | 0.945 | 0.260 | ||||
| Gyrification Index | ||||||||
| Right Hemisphere | 1.81 (0.02) | 1.76 (0.02) | 0.804 | 0.061 | ||||
| Left Hemisphere | 1.77 (0.02) | 1.75 (0.02) | 0.598 | 0.533 | ||||
| Cortical Surface Area (cm2) | ||||||||
| Right Hemisphere | 251.0 (5.1) | 249.1 (5.9) | 0.543 | 0.815 | ||||
| Left Hemisphere | 247.4 (4.9) | 246.6 (5.9) | 0.517 | 0.928 | ||||
Absolute volumes- estimated marginal means (SD), relative volumes - % [tissue type/TTV](SD)
p1- Unadjusted
p2- Adjusted for pma, propensity score, and MRI brain injury
p3-Adjusted for propensity score, and MRI brain injury