Table 3:
Effect of Surgical Duration on Volumetric and Cortical Surface Measures
| Surgical Duration | Surgical Duration | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No Surgery | Below Median | Above Median | p1 | p2 | No Surgery | Below Median | Above Median | p1 | p2 | |
| Tissue Volumes (cm3) | Absolute Volumes | Relative Volumes (%) | ||||||||
| White Matter | 133.2 (1.7) | 130.9 (3.0) | 121.5 (2.7) | 0.112 | 0.290 | 48.1 (3.2) | 47.0 (2.4) | 44.2 (3.7) | 0.001 | 0.002 |
| Cortical Gray Matter | 104.9 (1.7) | 107.8 (2.9) | 117.3 (2.9) | <0.001 | 0.128 | 37.4 (3.1) | 38.6 (2.7) | 42.3 (4.3) | <0.001 | 0.001 |
| DNGM | 22.9 (0.3) | 22.4 (0.6) | 21.5 (0.6) | 0.281 | 0.161 | 8.3 (.6) | 8.4 (0.7) | 7.7 (0.7) | 0.042 | 0.028 |
| Cerebellum | 16.9 (0.4) | 17.1 (0.7) | 16.2 (0.7) | 0.260 | 0.241 | 6.3 (.7) | 5.9 (.8) | 5.8 (1.0) | 0.076 | 0.732 |
| Total Tissue | 279.8 (5.1) | 263.2 (8.2) | 278.8 (9.2) | 0.062 | 0.244 | |||||
| Gyrification Index | ||||||||||
| Right Hemisphere | 1.82 (0.02) | 1.79 (0.04) | 1.73 (0.03) | 0.457 | 0.077 | |||||
| Left Hemisphere | 1.77 (0.19) | 1.79 (0.03) | 1.71 (0.03) | 0.481 | 0.228 | |||||
| Cortical Surface Area (cm2) | ||||||||||
| Right Hemisphere | 250.9 (5.1) | 240.6 (9.2) | 256.3 (8.5) | 0.011 | 0.484 | |||||
| Left Hemisphere | 247.0 (4.9) | 240.8 (8.6) | 252.6 (8.5) | 0.011 | 0.669 | |||||
Absolute volumes- estimated marginal means (SD), relative volumes - % [tissue type/TTV](SD)
p1- Unadjusted
p2- Adjusted for pma, propensity score, and MRI brain injury
p3- Adjusted for propensity score, and MRI brain injury