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STAT3 axis inhibition reversed the effect of IGF1 treatment on cell invasion of PTC cells. A, The cell invasive capacity of BCPAP and TPC1 cells after cotreatment with IGF1 (10 ng) and Cryp was analyzed by transwell invasion assay. B, The relative mRNA level of MMP‐2 and MMP‐9 in BCPAP and TPC1 cells after cotreatment with IGF1 (10 ng) and Cryp (10 µmol/L) was analyzed by qRT‐PCR *P < .05
