TABLE 2.
Potential biomarkers
| Potential biomarker | RT | CAS Number | DCIS vs healthy controls |
Lymph node metastasis‐ negative breast cancer vs healthy controls |
Lymph node metastasis‐ positive breast cancer vs healthy controls |
Breast cancer vs gastric cancer |
|---|---|---|---|---|---|---|
| a (S)‐1,2‐Propanediol | 3.04 | 4254‐15‐3 | o | o | o | o |
| a Cyclopentanone | 3.93 | 120‐92‐3 | o | o | o | o |
| Methyl acrylic acid | 4.46 | 79‐41‐4 | o | o | o | |
| Cyclohexanone | 6.15 | 108‐94‐1 | o | o | o | |
| 2‐Butoxyethanol | 6.36 | 111‐76‐2 | o | o | ||
| a Ethylene carbonate | 7.58 | 96‐49‐1 | o | o | o | o |
| a 3‐Methoxy‐1,2‐propanediol | 7.66 | 623‐39‐2 | o | o | ||
| a 3‐Methylpyridine | 8.04 | 108‐99‐6 | o | o | ||
| a Phenol | 8.06 | 108‐95‐2 | o | o | o | o |
| 1,1,3,3‐Tetramethylurea | 8.34 | 632‐22‐4 | o | o | o | |
| 2‐Ethylhexanol | 9.27 | 104‐76‐7 | o | o | o | |
| 2,6‐Dimethyloctane | 10.05 | 2051‐30‐1 | o | o | ||
| 2‐Phenyl‐2‐propanol | 10.57 | 617‐94‐7 | o | o | o | |
| a Tetramethyl silicane | 11.64 | 75‐76‐3 | o | o | o | o |
| Cyclohexanol, 2‐(1‐methylethyl)‐ | 12.51 | 96‐07‐1 | o | o | ||
| Hexamethyldisilane | 15.1 | 1450‐14‐2 | o | o | ||
| Propane, 2‐methyl‐1,2‐bis (trimethylsiloxy)‐ | 18.23 | 99875‐05‐5 | o | o |
Abbreviations: CAS, chemical abstracts service; DCIS, ductal carcinoma in situ; RT, retention time.
a
Indicates the biomarkers that were differentially detected between cohorts or subcohorts. o indicates that the compound was identified as a potential marker.