Table 4.

Results from linear mixed models depicting the percent changes in thyroid hormone concentrations associated with an interquartile range increase in PAH metabolite concentrations over the study period.

	TSH		T3		fT4
	%Δ (95% CI)	p-Value	%Δ (95% CI)	p-Value	%Δ (95% Cl)	p-Value
1-OH-NAI’	4.78 (−1.79, 11.8)	0.159	5.16 (2.12, 8.20)	0.001	1.40 (− 0.09, 2.89)	0.068
2-OH-NAP	−8.35 (−14.7, −1.58)	0.018	0.77 (−2.64, 4.18)	0.659	−1.00 (−2.64, 0.63)	0.230
1-OH-PYR	1.77 (−5.66, 9.80)	0.650	6.90 (3.34, 10.5)	0.000	0.93 (−0.81, 2.67)	0.296
2-OH-FLU	−1.92 (−8.45, 5.08)	0.582	3.98 (0.72, 7.25)	0.018	1.25 (−033, 2.84}	0.123
1-OH-PHE	1.14 (−5.53, 8.29)	0.744	7.99 (4.79, 11.2)	0.000	1.51 (−0.04, 3.07)	0.058
Σ2,3-OH-PHE	0(−6.74, 7.23)	1.000	3.29 (−0.02, 6.60)	0.053	0.15 (−1.46, 1.77)	0.853
	T4				T3/T4
	%Δ (95% CI)		p-Value		%Δ (95% CI)	p-Value
1-OH-NAP	−0.44 (−1.93, 1.06)		0.569		5.31 (2.15, 8.48)	0.001
2-OH-NAP	−0.71 (−2.37, 0.95)		0.402		1.51 (−2.02, 5.03)	0.404
1-OH-PYR	1.30 (−0.47, 3.07)		0.151		5.64 (1.92, 9.35)	0.003
2-OH-FLU	−0.90 (−2.50, 0.70)		0.273		5.42 (2.05, 8.8)	0.002
1-OH-PHE	0.21 (−1.39, 1.81)		0.796		7.98 (4.66, 11.31)	0.000
Σ2,3-OH-PHE	−0.63 (−2.25, 0.99)		0.449		4.58 (1.16, 8.01)	0.009

All models adjusted for continuous maternal age, categorical maternal education, categorical maternal exposure to environmental tobacco smoke, and specific gravity. Boldface indicates p-values of less than 0.055