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. 2020 Dec 9;8:610232. doi: 10.3389/fchem.2020.610232

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Copyright © 2020 Ma, Ma, Chen, Li, Liu, Ma, Mao, Yang, Ma and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The osteogenic differentiation of rabbit bone marrow-derived mesenchymal stem cells was assessed by RT-qPCR. The gene expression of OPN (a), Runx2 (b), BSP (c), VEGF (d), BMP 2 (e) in the blank group, β-TCP, and 8Cu-MSN-TCP scaffolds (n = 3). 8Cu-MSN-TCP scaffolds can recognize the promotion of osteogenesis.