Table 3.
Biological pathways enrichment of “host response signature network” using NDEx v2.4.5.
| Pathway Name | Pathway Properties | Number of overlap gene | p-value < | Similarity score |
|---|---|---|---|---|
| WP530—Cytokines and Inflammatory Response - Homo sapiens http://identifiers.org/wikipathways/WP530_r96982 Source: wikipathways |
Nodes:124; Egde:37 | 8 genes | 2.70e-10 | 0.21 |
| WP4341—Non-genomic actions of 1,25 dihydroxyvitamin D3 - Homo sapiens http://identifiers.org/wikipathways/WP4341_r107169 Source: WikiPathways |
Nodes:166; Egde:68 | 11 genes | 1e-12 | 0.19 |
| WP4197—The human immune response to tuberculosis - Homo sapiens http://identifiers.org/wikipathways/WP4197_r105840 Source: wikipathways |
Nodes:68; Egde:30 | 6 genes | 1.57e-8 | 0.20 |
| WP3617—Photodynamic therapy-induced NF-kB survival signaling - Homo sapiens http://identifiers.org/wikipathways/WP3617_r106541 Source WikiPathways |
Nodes: 59; Egde:12 | 9 genes | 1e-12 | 0.17 |
| WP4495—IL-10 Anti-inflammatory Signaling Pathway - Homo sapiens http://identifiers.org/wikipathways/WP4495_r102692 Source WikiPathways |
Nodes: 40; Egde:17 | 6 genes | 4.02e-12 | 0.16 |
| WP619—Type II interferon signaling (IFN-γ) - Homo sapiens http://identifiers.org/wikipathways/WP619_r106442 Source WikiPathways |
Nodes: 127; Egde:83 | 6 genes | 3.09e-7 | 0.13 |
| WP3624—Lung fibrosis - Homo sapiens http://identifiers.org/wikipathways/WP3624_r106633 Source: WikiPathways |
Nodes: 186; Egde:55 | 8 genes | 9.35e-11 | 0.12 |
| IL27-mediated signaling events Source: Pathway Interaction Database (PID) curated by NCI/Nature. |
Node: 26; Edge: 101 | 6 genes | 3.72e-10 | 0.11 |
| IL23-mediated signaling events Source: Pathway Interaction Database (PID) curated by NCI/Nature. |
Node: 37; Edge: 201 | 7 genes | 8.21e-11 | 0.11 |