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. 2020 Nov 25;23(12):101747. doi: 10.1016/j.isci.2020.101747

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Differential Expression of IL-7R Surface Expression and Elevated Neutrophil to Lymphocyte Ratio (NLR) in Simulated Deep Space Exposures

(A and B) Representative flow plot (NL-Sham control only) for lymphocytes within all events that have been doublet discriminated (DD) (A) and IL-7R median fluorescent intensity (MFI) histograms (NL- and HU-Sham only) within lymphocytes (B).

(C) MFI of IL-7R within lymphocytes is shown.

(D) Percentage (%) lymphocytes are displayed (SSC-A versus CD45⁺), as shown in Figure 1G.

(E) Neutrophil to lymphocyte ratio (NLR), a measurement of subclinical Paul et al., 2020 inflammation (Isaac et al., 2016), is shown. (C–E) Bar graph data represent means ± SEM (p < 0.05, n = 6–10 per group). Statistical tests and labels are the same as Figure 1.