Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The immunosenescence and inflammaging are interconnected. In immunosenescence, accumulation of senescent cells produce SASP, increased expression of inflammatory mediates of both immune cells and senescent cells and the insufficient downregulation of inflammation shift the body into the inflammaging state that results in further systemic inflammation and tissue damage, leading to several aged-related diseases.
