Table 1.

Summary of immune changes in immunosenescence.

Immunity	Cell	Changes	Study
Adaptive	T cell	- TCR pool diminishes	Kilpatrick et al. (10)
		- Subtype changes	Li et al. (11) Jagger et al. (12) Raynor et al. (13)
		- Inflammatory suppression weaken	Fessler et al. (14) Thomas et al. (15)
		- Pro-inflammatory mediates production increase	Hu et al. (16) Singh & Newman (17)
	B cell	- Subtype changes	Bulati et al. (18) Palma et al. (19)
		- Pro-inflammatory mediates production increase	Frasca & Blomberg (20)
Innate	Monocyte/macrophage	- Chemotaxis/phagocytosis decrease	Antonaci et al. (21) Mahbub et al. (22)
		- Subtype changes	Seidler et al. (23) Sadeghi et al. (24)
		- Pro-inflammatory mediates production increase	Sadeghi et al. (24) Olivieri et al. (25) Jacinto et al. (26)
	Dendritic cell	- Number decreases	Della et al. (27)
		- Pro-inflammatory mediates production increase	Splunter et al. (28)
	Microglia	- Subtype changes	Yao & Zhao (29)
		- Pro-inflammatory mediates production increase	Mecca et al. (30) Vida et al. (31)
	Neutrophils	- Chemotaxis/phagocytosis decrease	Niwa et al. (32)
	NK cell	- Number increase	Gounder et al. (33)
		- Pro-inflammatory mediates production increase	Camous et al. (34)