Figure 4.

Interaction between serum potassium levels and the study treatment. (A) Serum potassium (time‐updated, continuous) by study treatment. (B) Treatment effect throughout the spectrum of potassium concentration. Example illustrating the primary outcome associations (similar results are obtained for the other outcomes) i.e. no potassium by study treatment interaction (see also Table  2 ). CI, confidence interval; HR, hazard ratio; TTx effect, treatment effect of sacubitril–valsartan vs. enalapril.