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. 2020 Nov 16;97(1):15–29. doi: 10.1111/tan.14127

TABLE 2.

Top 10 haplotypes for each subpopulation and frequencies across all groups

Ethnicity Rank Haplotype Frequency in population
BI AS IN PA BA AF CA JE EA ME
BI 1 A*01:01 ~ C*07:01 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0841 0.0012 0.0005 0.0004 0.0033 0.0071 0.0178 0.0020 0.0068
2 A*03:01 ~ C*07:02 ~ B*07:02 ~ DRB1*15:01 ~ DQB1*06:02 0.0332 0.0017 0.0019 0.0008 0.0003 0.0036 0.0063 0.0016 0.0066
3 A*02:01 ~ C*05:01 ~ B*44:02 ~ DRB1*04:01 ~ DQB1*03:01 0.0297 0.0003 0.0003 0.0006 0.0010 0.0023 0.0032 0.0005 0.0031
4 A*02:01 ~ C*07:02 ~ B*07:02 ~ DRB1*15:01 ~ DQB1*06:02 0.0207 0.0009 0.0010 0.0012 0.0024 0.0021 0.0022
5 A*29:02 ~ C*16:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0201 0.0002 0.0006 0.0021 0.0081 0.0016
6 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0133 0.0195 0.0179 0.0211 0.0282 0.0005 0.0016 0.0022 0.0047 0.0039
7 A*02:01 ~ C*07:01 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0101 0.0002 0.0002 0.0003 0.0005 0.0008 0.0088 0.0012
8 A*03:01 ~ C*04:01 ~ B*35:01 ~ DRB1*01:01 ~ DQB1*05:01 0.0100 0.0037 0.0031 0.0028 0.0040 0.0011 0.0018 0.0012
9 A*02:01 ~ C*03:04 ~ B*15:01 ~ DRB1*04:01 ~ DQB1*03:02 0.0080 0.0002 0.0009 0.0012 0.0005 0.0017
10 A*24:02 ~ C*07:02 ~ B*07:02 ~ DRB1*15:01 ~ DQB1*06:02 0.0079 0.0024 0.0024 0.0026 0.0016 0.0007 0.0009 0.0003 0.0018
AS 1 A*26:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0259 0.0301 0.0388 0.0027 0.0001 0.0005 0.0022 0.0048
2 A*33:03 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0001 0.0226 0.0212 0.0134 0.0790 0.0010 0.0002 0.0102
3 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0133 0.0195 0.0179 0.0211 0.0282 0.0005 0.0016 0.0022 0.0047 0.0039
4 A*01:01 ~ C*06:02 ~ B*37:01 ~ DRB1*10:01 ~ DQB1*05:01 0.0016 0.0112 0.0133 0.0083 0.0136 0.0005 0.0007 0.0009 0.0044 0.0010
5 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0112 0.0108 0.0117 0.0063 0.0008 0.0007 0.0396 0.0024
6 A*02:11 ~ C*15:02 ~ B*40:06 ~ DRB1*15:01 ~ DQB1*06:01 0.0076 0.0083 0.0124 0.0045 0.0002 0.0011 0.0010
7 A*30:01 ~ C*06:02 ~ B*13:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0053 0.0073 0.0076 0.0095 0.0045 0.0007 0.0009 0.0115 0.0124 0.0076
8 A*11:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0006 0.0067 0.0077 0.0069 0.0204 0.0004 0.0115 0.0016 0.0042
9 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*13:02 ~ DQB1*06:09 0.0004 0.0054 0.0064 0.0030 0.0059 0.0013 0.0115 0.0003
10 A*01:01 ~ C*07:01 ~ B*15:17 ~ DRB1*13:02 ~ DQB1*06:04 0.0002 0.0047 0.0046 0.0060 0.0039 0.0001 0.0016 0.0033
IN 1 A*26:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0259 0.0301 0.0388 0.0027 0.0001 0.0005 0.0022 0.0048
2 A*33:03 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0001 0.0226 0.0212 0.0134 0.0790 0.0010 0.0002 0.0102
3 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0133 0.0195 0.0179 0.0211 0.0282 0.0005 0.0016 0.0022 0.0047 0.0039
4 A*01:01 ~ C*06:02 ~ B*37:01 ~ DRB1*10:01 ~ DQB1*05:01 0.0016 0.0112 0.0133 0.0083 0.0136 0.0005 0.0007 0.0009 0.0044 0.0010
5 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0112 0.0108 0.0117 0.0063 0.0008 0.0007 0.0396 0.0024
6 A*02:11 ~ C*15:02 ~ B*40:06 ~ DRB1*15:01 ~ DQB1*06:01 0.0076 0.0083 0.0124 0.0045 0.0002 0.0011 0.0010
7 A*11:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0006 0.0067 0.0077 0.0069 0.0204 0.0004 0.0115 0.0016 0.0042
8 A*30:01 ~ C*06:02 ~ B*13:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0053 0.0073 0.0076 0.0095 0.0045 0.0007 0.0009 0.0115 0.0124 0.0076
9 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*13:02 ~ DQB1*06:09 0.0004 0.0054 0.0064 0.0030 0.0059 0.0013 0.0115 0.0003
10 A*01:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0037 0.0048 0.0055 0.0001 0.0058
PA 1 A*26:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0259 0.0301 0.0388 0.0027 0.0001 0.0005 0.0022 0.0048
2 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0133 0.0195 0.0179 0.0211 0.0282 0.0005 0.0016 0.0022 0.0047 0.0039
3 A*33:03 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0001 0.0226 0.0212 0.0134 0.0790 0.0010 0.0002 0.0102
4 A*02:11 ~ C*15:02 ~ B*40:06 ~ DRB1*15:01 ~ DQB1*06:01 0.0076 0.0083 0.0124 0.0045 0.0002 0.0011 0.0010
5 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0112 0.0108 0.0117 0.0063 0.0008 0.0007 0.0396 0.0024
6 A*30:01 ~ C*06:02 ~ B*13:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0053 0.0073 0.0076 0.0095 0.0045 0.0007 0.0009 0.0115 0.0124 0.0076
7 A*32:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0035 0.0024 0.0089
8 A*01:01 ~ C*06:02 ~ B*37:01 ~ DRB1*10:01 ~ DQB1*05:01 0.0016 0.0112 0.0133 0.0083 0.0136 0.0005 0.0007 0.0009 0.0044 0.0010
9 A*11:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0006 0.0067 0.0077 0.0069 0.0204 0.0004 0.0115 0.0016 0.0042
10 A*01:01 ~ C*07:01 ~ B*15:17 ~ DRB1*13:02 ~ DQB1*06:04 0.0002 0.0047 0.0046 0.0060 0.0039 0.0001 0.0016 0.0033
BA 1 A*33:03 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0001 0.0226 0.0212 0.0134 0.0790 0.0010 0.0002 0.0102
2 A*11:01 ~ C*08:01 ~ B*15:02 ~ DRB1*12:02 ~ DQB1*03:01 0.0031 0.0008 0.0013 0.0308 0.0001 0.0221
3 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0133 0.0195 0.0179 0.0211 0.0282 0.0005 0.0016 0.0022 0.0047 0.0039
4 A*11:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0006 0.0067 0.0077 0.0069 0.0204 0.0004 0.0115 0.0016 0.0042
5 A*01:01 ~ C*06:02 ~ B*37:01 ~ DRB1*10:01 ~ DQB1*05:01 0.0016 0.0112 0.0133 0.0083 0.0136 0.0005 0.0007 0.0009 0.0044 0.0010
6 A*11:01 ~ C*08:01 ~ B*15:02 ~ DRB1*15:01 ~ DQB1*06:01 0.0018 0.0011 0.0028 0.0135 0.0062
7 A*02:03 ~ C*08:01 ~ B*15:02 ~ DRB1*15:02 ~ DQB1*05:01 0.0008 0.0006 0.0090 0.0002
8 A*24:02 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0019 0.0017 0.0004 0.0082 0.0003
9 A*11:01 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0041 0.0040 0.0039 0.0073 0.0015
10 A*24:02 ~ C*07:02 ~ B*07:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0004 0.0017 0.0013 0.0015 0.0064 0.0002 0.0013
AF 1 A*30:01 ~ C*17:01 ~ B*42:01 ~ DRB1*03:02 ~ DQB1*04:02 0.0002 0.0006 0.0130 0.0145 0.0001 0.0014
2 A*36:01 ~ C*04:01 ~ B*53:01 ~ DRB1*11:01 ~ DQB1*06:02 0.0111 0.0102
3 A*33:03 ~ C*04:01 ~ B*53:01 ~ DRB1*08:04 ~ DQB1*03:01 0.0103 0.0086
4 A*34:02 ~ C*04:01 ~ B*44:03 ~ DRB1*15:03 ~ DQB1*06:02 0.0086 0.0071
5 A*66:02 ~ C*07:01 ~ B*58:01 ~ DRB1*15:03 ~ DQB1*06:02 0.0066 0.0044
6 A*68:01 ~ C*06:02 ~ B*58:02 ~ DRB1*12:01 ~ DQB1*05:01 0.0047 0.0067
7 A*68:02 ~ C*03:04 ~ B*15:10 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0040 0.0044
8 A*36:01 ~ C*04:01 ~ B*53:01 ~ DRB1*15:03 ~ DQB1*06:02 0.0037 0.0019
9 A*30:01 ~ C*17:01 ~ B*42:01 ~ DRB1*08:04 ~ DQB1*03:01 0.0037 0.0037 0.0003
10 A*23:01 ~ C*07:02 ~ B*07:02 ~ DRB1*09:01 ~ DQB1*02:01 0.0036 0.0040
CA 1 A*30:01 ~ C*17:01 ~ B*42:01 ~ DRB1*03:02 ~ DQB1*04:02 0.0002 0.0006 0.0130 0.0145 0.0001 0.0014
2 A*36:01 ~ C*04:01 ~ B*53:01 ~ DRB1*11:01 ~ DQB1*06:02 0.0111 0.0102
3 A*33:03 ~ C*04:01 ~ B*53:01 ~ DRB1*08:04 ~ DQB1*03:01 0.0103 0.0086
4 A*34:02 ~ C*04:01 ~ B*44:03 ~ DRB1*15:03 ~ DQB1*06:02 0.0086 0.0071
5 A*01:01 ~ C*07:01 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0841 0.0012 0.0005 0.0004 0.0033 0.0071 0.0178 0.0020 0.0068
6 A*68:01 ~ C*06:02 ~ B*58:02 ~ DRB1*12:01 ~ DQB1*05:01 0.0047 0.0067
7 A*68:02 ~ C*03:04 ~ B*15:10 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0040 0.0044
8 A*66:02 ~ C*07:01 ~ B*58:01 ~ DRB1*15:03 ~ DQB1*06:02 0.0066 0.0044
9 A*23:01 ~ C*07:02 ~ B*07:02 ~ DRB1*09:01 ~ DQB1*02:01 0.0036 0.0040
10 A*30:01 ~ C*17:01 ~ B*42:01 ~ DRB1*08:04 ~ DQB1*03:01 0.0037 0.0037 0.0003
JE 1 A*26:01 ~ C*12:03 ~ B*38:01 ~ DRB1*04:02 ~ DQB1*03:02 0.0006 0.0001 0.0528 0.0014
2 A*33:01 ~ C*08:02 ~ B*14:02 ~ DRB1*01:02 ~ DQB1*05:01 0.0022 0.0014 0.0016 0.0016 0.0006 0.0008 0.0222 0.0006 0.0124
3 A*24:02 ~ C*04:01 ~ B*35:02 ~ DRB1*11:04 ~ DQB1*03:01 0.0010 0.0032 0.0034 0.0049 0.0003 0.0212 0.0087
4 A*01:01 ~ C*04:01 ~ B*35:02 ~ DRB1*11:04 ~ DQB1*06:03 0.0002 0.0199 0.0002 0.0017
5 A*68:02 ~ C*08:02 ~ B*14:02 ~ DRB1*01:02 ~ DQB1*05:01 0.0003 0.0193
6 A*01:01 ~ C*07:01 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0841 0.0012 0.0005 0.0004 0.0033 0.0071 0.0178 0.0020 0.0068
7 A*01:01 ~ C*06:02 ~ B*57:01 ~ DRB1*13:05 ~ DQB1*03:01 0.0002 0.0177
8 A*02:01 ~ C*04:01 ~ B*35:03 ~ DRB1*12:01 ~ DQB1*03:01 0.0003 0.0177
9 A*03:01 ~ C*12:03 ~ B*38:01 ~ DRB1*13:01 ~ DQB1*06:03 0.0004 0.0003 0.0003 0.0163 0.0007
10 A*02:05 ~ C*06:02 ~ B*50:01 ~ DRB1*07:01 ~ DQB1*02:01 0.0029 0.0044 0.0046 0.0024 0.0005 0.0002 0.0120 0.0016 0.0088
EA 1 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0001 0.0112 0.0108 0.0117 0.0063 0.0008 0.0007 0.0396 0.0024
2 A*02:07 ~ C*01:02 ~ B*46:01 ~ DRB1*09:01 ~ DQB1*03:03 0.0006 0.0303
3 A*11:01 ~ C*08:01 ~ B*15:02 ~ DRB1*12:02 ~ DQB1*03:01 0.0031 0.0008 0.0013 0.0308 0.0001 0.0221
4 A*30:01 ~ C*06:02 ~ B*13:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0053 0.0073 0.0076 0.0095 0.0045 0.0007 0.0009 0.0115 0.0124 0.0076
5 A*33:03 ~ C*03:02 ~ B*58:01 ~ DRB1*13:02 ~ DQB1*06:09 0.0004 0.0054 0.0064 0.0030 0.0059 0.0013 0.0115 0.0003
6 A*33:03 ~ C*07:01 ~ B*44:03 ~ DRB1*07:01 ~ DQB1*02:01 0.0001 0.0226 0.0212 0.0134 0.0790 0.0010 0.0002 0.0102
7 A*11:01 ~ C*01:02 ~ B*46:01 ~ DRB1*09:01 ~ DQB1*03:03 0.0002 0.0083
8 A*02:03 ~ C*07:02 ~ B*38:02 ~ DRB1*16:02 ~ DQB1*05:02 0.0005 0.0002 0.0003 0.0072
9 A*11:01 ~ C*07:02 ~ B*40:01 ~ DRB1*09:01 ~ DQB1*03:03 0.0001 0.0067
10 A*11:01 ~ C*03:04 ~ B*13:01 ~ DRB1*15:01 ~ DQB1*06:01 0.0002 0.0067
ME 1 A*33:01 ~ C*08:02 ~ B*14:02 ~ DRB1*01:02 ~ DQB1*05:01 0.0022 0.0014 0.0016 0.0016 0.0006 0.0008 0.0222 0.0006 0.0124
2 A*01:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0017 0.0023 0.0016 0.0036 0.0037 0.0004 0.0034 0.0011 0.0089
3 A*02:05 ~ C*06:02 ~ B*50:01 ~ DRB1*07:01 ~ DQB1*02:01 0.0029 0.0044 0.0046 0.0024 0.0005 0.0002 0.0120 0.0016 0.0088
4 A*24:02 ~ C*04:01 ~ B*35:02 ~ DRB1*11:04 ~ DQB1*03:01 0.0010 0.0032 0.0034 0.0049 0.0003 0.0212 0.0087
5 A*30:01 ~ C*06:02 ~ B*13:02 ~ DRB1*07:01 ~ DQB1*02:01 0.0053 0.0073 0.0076 0.0095 0.0045 0.0007 0.0009 0.0115 0.0124 0.0076
6 A*01:01 ~ C*07:01 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0841 0.0012 0.0005 0.0004 0.0033 0.0071 0.0178 0.0020 0.0068
7 A*03:01 ~ C*07:02 ~ B*07:02 ~ DRB1*15:01 ~ DQB1*06:02 0.0332 0.0017 0.0019 0.0008 0.0003 0.0036 0.0063 0.0016 0.0066
8 A*01:01 ~ C*07:02 ~ B*08:01 ~ DRB1*03:01 ~ DQB1*02:01 0.0037 0.0048 0.0055 0.0001 0.0058
9 A*01:01 ~ C*17:01 ~ B*41:01 ~ DRB1*07:01 ~ DQB1*03:03 0.0003 0.0004 0.0001 0.0003 0.0004 0.0056
10 A*02:01 ~ C*12:02 ~ B*52:01 ~ DRB1*15:02 ~ DQB1*06:01 0.0005 0.0020 0.0021 0.0031 0.0007 0.0003 0.0086 0.0050

Abbreviations: AF, African; AS, Asian; BA, Bangladesh; BI, BINWE; CA, African Caribbean; EA, East Asian; IN, India; JE, Jewish; ME, Middle Eastern; PA, Pakistan.