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L. amazonensis parasite's plasma membrane permeabilization induced by treatment with gold complexes. A) 4×106 promastigotes and B) 8×106 axenic amastigotes were incubated with EC50 of AMB, 3, 6 and 7 at neutral and acidic pH, respectively, for 3 h (dashed lines) and 24 h (solid lines). I: addition of 10 mM ethidium bromide; II: addition of digitonin at 100 mM.
