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. 2020 Oct 7;41(32):2740–2749. doi: 10.1002/jcc.26426

TABLE 1.

Statistical analysis on the significance of differences. p‐Values obtained from a multivariate multilevel analysis on 52 proteins with 3 replicates each

CG/TR vs. CG/SR CG/TR vs. AT/TR
Property Significance p‐Value Significance p‐Value
RMSD100 1 *** <.0001
No. H‐bondbackbone .3757 *** <.0001
SASApolar 1 *** <.0001
Radius of gyration 1 ** .0078
NOE violations a 1 * .0151
J‐value a 1 .8488
SASAnonpolar .14444 1
Occurrence of α‐helix 1 · .0780
Occurrence of π‐helix 1 .5290
Occurrence of 310‐helix 1 1
Occurrence of β‐strand 1 1
Occurrence of β‐bridge 1 1

Abbreviations: AT, atomistic; CG, charge‐group based; SR, single range; TR, twin range.

a

NMR data are available for a subset of 13 proteins.