Table 1.
Effects of valencene derivatives on ITRPV1 and IORAI1 at 90 µM
| Compound | (I/Icon × 100%) ± SEM (n) | |
|---|---|---|
| ITRPV1 at –60 mV | IORAI1 at –120 mV | |
| Controla | 100 | 100 |
| Valencene (Nam et al. [18], 2016) |
31.2 ± 15.73 (3) | 5.58 ± 2.12 (4) |
| Nootkatol | 6.3 ± 2.36 (7) | 3.4 ± 1.43 (4) |
| Nootkatone | 176.2 ± 18.01 (3) | 53.4 ± 7.86 (5) |
| Valencene-13-aldehyde | 53.9 ± 9.59 (4) | 57.1 ± 7.78 (6) |
| Decaline | 139.5 ± 11.07 (4) | 87.5 ± 5.71 (5) |
Values in parentheses are the total number (n) of experiments at each concentration. Data represent remaining current compared to control, normalized to 100%, and are presented as the mean ± standard error of the mean (SEM). aControl indicates the normalized value at the steady-state peak current before treatment with compounds.