TABLE 1.
Background characteristics in 116 cases of epilepsy with onset before 2 years
|
Onset age <12 mo, n (%) |
Onset age >12 mo, n (%) |
Age difference, P‐value, significance at P < .05 |
All cases, onset age <24 mo, n (%) |
|
|---|---|---|---|---|
| All | 88/88 (100) | 28/28 (100) | 116/116 (100) | |
| Gender, female | 45/88 (51) | 12/28 (43) | Ns | 57/116 (49) |
| Epilepsy first‐degree relative | 18/88 (20) | 1/27 (3.7) | ns, P = .08 a | 19/115 (17) |
| Febrile seizures first‐degree relative | 2/83 (2.4) | 22 (5/23) | P = .005 b | 7/106 (6.6) |
| Type of birth: section | 24/86 (28) | 5/28 (18) | ns | 29/114 (25) |
| Gestation: <37 wk | 7/88 (8.0) | 2/28 (7.1) | ns | 9/116 (7.8) |
| Birth weight: <2.5 kg | 7/83 (8.4) | 2/24 (8.3) | ns | 9/107 (8.4) |
| Acute symptomatic seizures | 16/88 (18) | 4/28 (14) | ns | 20/116 (17) |
| Febrile before afebrile seizure | 8/88 (9.1) | 15/28 (54) | P < .001 c | 23/116 (20) |
| Developmental delay at onset | 34/88 (39) | 12/28 (43) | ns | 46/116 (40) |
Onset refers to the first unprovoked seizure. n, number of cases (% of all cases). Difference between age groups: chi‐square test with Yates correction. ns, non‐significant = P > .05.
a
P = .13 if GEFS+ cases are excluded.
b
P = .92 and not significant if GEFS+ excluded.
c
Still significant, P < .001, if GEFS+ and Dravet excluded.