(A) Hepatic mRNA levels of cell cycle regulators. (B) Immunoblot analysis of cyclin B1, cyclin D1 and c-Fos. (C-D) Immunoblot analysis of STAT3, ERK1/2 and JNK1/2. (E) Hepatic mRNA levels of AP-1 (Fos and Jun) and Jnk1/2. Data are expressed as meanĀ±S.E.M. *P<.05, **P<.01, and ***P<.001 between control diet-fed and SFA-rich diet-fed HCVcpTg mice. Con, control diet-fed HCVcpTg mice; SFA, SFA-rich diet-fed HCVcpTg mice.