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EGFR expression in HNSCC cells grown in 3D ± CAFs after treatment with cisplatin and cetuximab. Expression of epidermal growth factor receptor (EGFR) in response to treatment with cetuximab and cisplatin was measured in 5 days old tumor spheroids by immunohistochemical staining. Untreated spheroids (a, b). Cetuximab treated spheroids (c, d). Cisplatin treated spheroids (E, F). Scale bar = 150 µm
