Table 2.

βII spectrin in other diseases

Disease Type	Changes in βII spectrin	References
Arrhythmia	βII spectrin downregulation	17, 112
Heart failure (HF)	No change	113
Myeloproliferative disease (MPD)	SPTBN1-PDGFRB: chemotherapy target	117
Osteoporosis	Variation in SPTBN1 expression	12, 118-121, 123-128, 149
Neurodegenerative diseases	βII spectrin mutation	137
HIV	βII spectrin upregulation	140
Primary congenital glaucoma (GLC3)	Related candidate gene	143
Beckwith-Wiedemann syndrome (BWS)	Loss of βII spectrin	93