Table 1.
PTM proteins sorting into exosomes. The residues were marked in the brackets
Group | Target Protein(protein residues) |
---|---|
Ubiquitination | Histone H1.2; HLA-G complex;ARRDC1-(Lys, N-terminus, non-lysine residues (Cys, Thr, Ser)); LMP2A-(Lys, N-terminus, non-lysine residues (Cys, Thr, Ser)); PTEN-(Lys, N-terminus, non-lysine residues (Cys, Thr, Ser)); hsp70-(Lys, N-terminus, non-lysine residues (Cys, Thr, Ser)); SIMPLE-(Lys, N-terminus, non-lysine residues (Cys, Thr, Ser)); Aquaporin-1; Annexin A1; Plastin-3 isoform 1; hspX; GroES; GFP; ATG85B-ESAT6; nHer2; MHC-II; Tsg101; Hrs Epsin; Rabex; Eps15; Fas Ligand. |
Phosphorylation | CryAB; Tau; EGFR; IRS-1; PDK1; AKT; SRC; ELK1; ERK 1/2; AMPKα1; Acetyl-CoA carboxylase; NCC; Aquaporin 2; GPRC5C; CHMP2B; Annexin A2-(Tyr,Thr,Ser,His); tau-(Tyr,Thr,Ser,His); Fas Ligand-(Tyr,Thr,Ser,His); γ-synuclein-(Tyr,Thr,Ser,His). |
SUMOylation | GFP; α-synuclein; hnRNPA2B1 |
ISGylation | Tsg101 |
Oxidation | γ-synuclein |
Acetylation | GRP78 |
Citrullination | Vimentin |
Myristoylation | TyA-(N-terminal glycine residue) |
Glycosylation | LGALS3BP, CD82-(Asn157) |
GPI-anchor | CD55 |
FAT10ylation | FAT10-(carboxyl-terminal GlyGly) |