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. 2021 Jan 1;17(1):220–235. doi: 10.7150/ijbs.50730

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Potential Clinical Applications of LncRNAs as Biomarkers for Diagnosis and Treatment of HCC. LncRNAs can be used as an indicator to distinguish benign and malignant tumors. Serum lncRNAs can be used as potential biomarkers for HCC diagnosis, or be used as one of the reference conditions for clinicians to choose suitable therapeutic strategy. Continuous collection of blood samples and check the types and levels of serum lncRNA during treatment can be an important indicator of the effectiveness of treatment, as well as monitoring disease progression and predicting the prognosis of HCC patients.