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. 2020 Dec 8;45(2):481–492. doi: 10.3892/or.2020.7886

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Copyright: © An et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — TGF-β1 promotes OVCAR433 cell progression. A TGF-β1 overexpression plasmid was transfected into KRT7 knockdown OVCAR433 cells. (A) Protein expression levels of KRT7, TGF-β1, Smad2/3 and p-Smad2/3. *P<0.05 vs. shKRT7/ctrl vector. (B) Transwell assays were used to detect cell migration. Magnification, ×100. (C) Wound healing assays were performed to assess cell migration. Magnification, ×100. (D) Colony formation assays were performed to detect cell proliferation. **P<0.01. p-, phosphorylated; KRT7, keratin 7; sh, short hairpin RNA; Ctrl, control.