Skip to main content
. 2020 Dec 2;45(2):513–522. doi: 10.3892/or.2020.7879

Figure 1.

Figure 1.

Polyphyllin VII affects A2780 and SKOV3 cells in a dose-dependent manner. (A) Chemical structure of polyphyllin VII. (B and C) A2780 and SKOV3 cells were treated with various concentrations of polyphyllin VII for 24 h. The viability of A2780 and SKOV3 cells was measured by MTT assay. (D) Detection of A2780 and SKOV3 cell apoptotic fractions using Annexin V/propidium iodide staining. (E) Western blot analysis of cleaved caspase-3 (c-caspase-3) in A2780 and SKOV3 cells after polyphyllin VII treatment. Results are shown as mean ± SD from three independent experiments performed in triplicate. *P<0.05, **P<0.01, ***P<0.001, compared with the control (0 µM).