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. 2020 Dec 2;45(2):513–522. doi: 10.3892/or.2020.7879

Figure 2.

Figure 2.

Polyphyllin VII promotes mitochondrial dysfunction in A2780 and SKOV3 cells. (A) DCFH-DA was used to evaluate ROS in A2780 and SKOV3 cells after polyphyllin VII treatment. (B) JC-1 was used to evaluate Dym in A2780 and SKOV3 cells after polyphyllin VII treatment. (C) Western blot analysis of BCL-2 and BAX in A2780 and SKOV3 cells after polyphyllin VII treatment. Results are shown as mean ± SD from three independent experiments performed in triplicate. *P<0.05, **P<0.01, #P<0.001, compared with the control (0 µM).