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RUNX1C+ Hematopoietic Progenitors Emerge from SOX17+ Hemogenic Endothelium
Confocal images at day 17 of the adherent EB cultures. RUNX1C+ blood progenitors arise from hematopoietic cell clusters within vascular structures of SOX17+ hemogenic endothelium (arrows), mimicking the structures observed in the embryonic AGM. Bottom right image contains merged layers of a Z-stack capture. Scale bar represents 200 μm, 100 μm or 50 μm as indicated. SOX17 (mCHERRY, red) and RUNX1C (GFP, green).
