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. 2021 Jan 1;18(2):406–418. doi: 10.7150/ijms.47706

Figure 3.

Figure 3

The “Fast DC” emerges and develops with the altered cytokine cocktails. A). Cultured with GM-CSF, IL-4 (1 day) and IL-1β, TNF-α, IFN-γ Mo-driven DC subsets are able to activate Th 1 cell response. B). The population produced through GM-CSF, IL-4 (1 day) and IL-1β, TNF-α, IL-6, PGE2(1 day) promote differentiation of CD4+ T cells towards a Th 2 cell phenotype. C). Cytokines including TNF-α, IL-10, IL-6, IL-21, IL27, TGF-β induce generation of DC subsets that promote the differentiation of Treg cell.