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PIGR expression in HCC tissues and serum samples. PIGR mRNA was significantly upregulated in Guichard Liver, Guichard Liver 2 and TCGA Liver in Oncomine database (A), and in GSE55092 and GSE60502 in GEO database (B); PIGR mRNA was significantly overexpressed in HCC PBMC samples compared to that in healthy individuals (C); PIGR protein was highly expressed in HCC tumor tissues compared to that in normal liver tissues (D).* p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
