Table 1.
Study characteristics and hemorrhagic shock protocols
| Species | Studies (number) | Sex (male/ female/ both/ ND) | Group size (number) | Weight range (g) | Hemorrhagic shock protocol | Resuscitation protocol | References | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pressure/ volume controlled | Target MAP (mm Hg) | Duration HS (min) | Trauma (number) | Resuscitation fluid (number) | Follow‐up (min) | ||||||
| Rat | 37 | 28/ 6/ 0/ 3 | 4‐26 | 150‐390 | 35/ 2 | 25‐65 | 15‐120 | 18 | Blood (4), crystalloid (17), Blood + crystalloid (16) | 30‐24 h | (13, 19, 21, 22, 23, 24, 25, 26, 27, 28, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 45, 49, 50, 51, 52, 53, 55, 58, 61, 62, 63, 64, 65 |
| Dog | 4 | 0/ 1/ 1/ 2 | 5‐15 | 15 500‐36000 | 3/ 1 | 30‐50 | 60‐210 | 2 | Blood (2), colloid (1), Blood + crystalloid (1) | 60‐180 | (46, 47, 48, 59 |
| Hamster | 6 | 6/ 0/ 0/ 0 | 5‐10 | 55‐140 | 3/ 3 | 30‐60 | 45‐60 | 1 | Blood (3), crystalloid (2), colloid (1) | 60‐120 | (29, 44, 54, 56, 57, 60 |
| Pig | 1 | 0/ 0/ 0/ 1 | 10 | 8000‐12 000 | 0/ 1 | 50 | ND | 0 | Crystalloid (1) | ND | (20) |
Study characteristics of included studies.
Abbreviations: HS, hemorrhagic shock; MAP, mean arterial pressure; ND, not determined.