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. 2020 Nov 16;1(3):100167. doi: 10.1016/j.xpro.2020.100167

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© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Effect of Snap Freezing and Rapid Thawing on Tissue Stiffness Measurements

(A) Quantification of tissue stiffness in fresh primary tumor (Fresh pTU) and liver metastases tissue (Fresh LM) (n = 6 Fresh pTU/4 Fresh LM; p = 0.0017; t = 4.627, df = 8).

(B) Quantification of tissue stiffness in Rapid Freeze-Rapid Thaw primary tumor (Cryo pTU) and liver metastases (Cryo LM) (n = 6 Cryo pTU/4 Cryo LM; p < 0.0001; t = 8.235, df = 8).

(C) Pearson correlation between Fresh pTU and Cryo pTU (n = 6; r = 0.9255; p = 0.0081).

(D) Pearson correlation between Fresh LM and Cryo LM (n = 4; r = 0.9686; p = 0.0314). Displayed dots are the average of 3 measurements. Figure modified from Shen et al. (2020).