Table 2.
Demographic and clinical characteristics of patients diagnosed with multiple myeloma according to blood groups
| Clinical features | A (n = 92) | 0 (n = 49) | B (n = 38) | AB (n = 19) | P | P A vs. non‑A | P 0 vs. non‑0 | P B vs. non‑B | P AB vs. non-AB |
|---|---|---|---|---|---|---|---|---|---|
| Gender F/M n/n, (%/%) | 49/43 (53.3/46.7) | 24/25 (49.0/51.0) | 13/25 (34.2/65.8) | 6/13 (31.6/68.4) | 0.121 | 0.087 | 0.742 | 0.105 | 0.228 |
| Age med. at the time of diagnosis | 62 (36–90) | 63 (32–87) | 66 (41–79) | 62 (41–79) | 0.548 | 0.636 | 0.809 | 0.166 | 0.487 |
| Heavy chain type n (%) | – | – | – | – | 0.039 | 0.021 | 0.379 | 0.277 | 0.479 |
| G | 50 (54.3) | 24 (49.0) | 26 (68.4) | 11 (57.9) | – | – | – | – | – |
| A | 32 (34.8) | 14 (28.6) | 4 (10.5) | 2 (10.5) | – | – | – | – | – |
| M | 0 (0) | 1 (2.0) | 0 (0.0) | 0 (0.0) | – | – | – | – | – |
| Non‑G, A, M | 10 (10.9) | 10 (20.4) | 8 (21.1) | 6 (31.6) | – | – | – | – | – |
| Light chain type n (%) | – | – | – | 0.048 | 0.032 | 0.059 | 0.748 | 0.092 | |
| K | 59 (64.1) | 20 (40.8) | 22 (57.9) | 8 (42.1) | – | – | – | – | – |
| L | 33 (35.9) | 28 (57.1) | 16 (42.1) | 10 (52.6) | – | – | – | – | – |
| Non‑K, L | 0 (0.0) | 1 (2.1) | 0 (0.0) | 1 (5.3) | – | – | – | – | – |
| LDH> normal n (%) | 23 (25.0) | 23 (46.9) | 9 (23.7) | 6 (31.6) | 0.039 | 0.123 | 0.007 | 0.333 | 1.000 |
| Beta‑2 microglobulin med | 4.69 (1.2–59.4) | 5.51 (1.51–42.3) | 4.49 (1.8–61.3) | 5.64 (1.6–27.3) | 0.654 | 0.223 | 0.129 | 0.841 | 0.671 |
| Hypercalcemia n (%) | 11 (12.0) | 9 (18.4) | 3 (7.9) | 3 (15.8) | 0.509 | 0.679 | 0.227 | 0.424 | 0.721 |
| Renal Impairment n (%) | 21 (22.8) | 17 (34.7) | 8 (21.1) | 8 (42.1) | 0.163 | 0.204 | 0.198 | 0.420 | 0.173 |
| Anemia n (%) | 64 (69.6) | 41 (83.7) | 24 (63.2) | 15 (78.9) | 0.363 | 0.403 | 0.132 | 0.271 | 0.789 |
| Lytic lesion n (%) | 80 (87.0) | 42 (85.7) | 30 (78.9) | 17 (89.5) | 0.637 | 0.688 | 1.000 | 0.211 | 1.000 |
| Extramedullary lesion n (%) | 8 (8.6) | 17 (34.7) | 3 (7.9) | 2 (10.5) | 0.000 | 0.082 | 0.000 | 0.305 | 1.000 |
F Female, M Male, Med median, K Kappa, L Lambda, LDH Lactate dehydrogenase