Mice Subjected to TAC Developed Clinical Heart Failure
(A and B) Representative Masson’s trichrome staining of myocardial fibrosis, as in (B). Blue indicates the accumulation of extracellular matrix or fibrosis; quantitative data (B) is on the right. Magnification: ×20. n = 6. Scale, 20 μm.
(C and D) Representative images of wheat germ agglutinin (WGA) staining for confirming cardiomyocyte dilation; quantitative data (D) is on the right. n = 6. Scale bar, 20 μm. Data presented as means ± SE; ∗p < 0.05 versus sham.