Table 1.
Subject Demographics
| |
Control (n = 37) |
cMild/mod (n = 10) |
severe (n = 18) |
Control vs. cMild/mod |
Control vs. severe |
cMild/mod vs. severe |
|---|---|---|---|---|---|---|
| mean (SD) | mean (SD) | mean (SD) | p | p | p | |
| Age at injury (years) | 13.5 (3.2) | 12.0 (3.6) | 12.2 (3.6) | ns | ns | ns |
| [range] | [5.5 – 17.4] | [5.8 – 16.9] | [5.0 – 17.8] | |||
| Sex (M/F) | 20/17 | 9/1 | 12/6 | ns | ns | ns |
| Days to MRI (days) | 12.5 (4.1) | 11.1 (3.5) | - | ns | ns | |
| [range] | [8.0 – 18.0] | [6.0 – 17.0] | ||||
| Months to follow-up | 12.9 (1.1) | 12.1 (0.9) | 12.5 (0.7) | ns | ns | ns |
| [range] | [11.7 – 16.7] | [10.8 – 13.8] | [11.3 – 13.9] | |||
| Injury characteristics | ||||||
| LOC >24 h (%) | NA | 0 | 39.1 | |||
| Days in coma | NA | 2.4 (3.4) | 3.8 (4.1) | ns | ns | ns |
| [range] | [0 – 11] | [1 – 12] | ||||
| Days on ventilator | NA | 2.3 (3.1) | 3.7 (4.2) | ns | ns | ns |
| [range] | [0 – 9] | [0 – 14] | ||||
| Days in hospital | NA | 10.5 (6.2) | 14.5 (8.9) | ns | ns | ns |
| [range] | [4 – 23] | [3 – 29] | ||||
| 12-month neurological and neuropsychological testing scores | ||||||
| PCPCS | 1.0 | 1.3 (0.5) | 1.4 (0.7) | < 0.001 | < 0.001 | ns |
| VIQ | 107.4 (13.7) | 94.1 (10.4) | 90.8 (15.2) | 0.025 | < 0.001 | ns |
| PIQ | 107.2 (14.0) | 99.8 (14.1) | 98.5 (10.1) | ns | ns | ns |
| FSIQ | 107.9 (13.4) | 95.7 (10.4) | 94.1 (12.9) | 0.031 | 0.002 | ns |
| Combined memory Z score | 122.1 (15.3) | 101.3 (24.5) | 102.0 (20.1) | 0.022 | 0.005 | ns |
| TEA-CH C attention | 11.1 (3.6) | 9.3 (3.2) | 9.3 (2.8) | ns | ns | ns |
| TEA-CH G attention | 11.3 (3.8) | 9.9 (2.7) | 9.5 (3.4) | ns | ns | ns |
SD, standard deviation; cMild/mod, complicated mild/moderate TBI; ns, nonsignificant ; M, male; F female; MRI, magnetic resonance imaging; LOC, loss of consciousness; PCPCS, pediatric cerebral performance category scale; VIQ, verbal IQ; PIQ, performance IQ; FSIQ, full scale IQ; TEA-Ch, test of everyday attention-for children;