Table 11.
Flow rate | Lifestage | Active | Product | MB (%), mean (SD) | ISM (μg), mean (SD) | FPM (μg), mean (SD) | MMAD (μm), mean (SD) | GSD (μm), mean (SD) |
---|---|---|---|---|---|---|---|---|
30 | BoL | FP | Test | 95.2 (4.4) | 51.5 (4.7) | 33.9 (3.2) | 4.2 (0.1) | 1.9 (0.0) |
Ref | 99.9 (7.0) | 53.2 (3.8) | 38.7 (3.1) | 3.7 (0.2) | 2.0 (0.0) | |||
Sal | Test | 100.1 (3.8) | 8.3 (0.7) | 5.3 (0.5) | 4.4 (0.1) | 1.8 (0.0) | ||
Ref | 101.2 (7.5) | 9.3 (0.8) | 6.5 (0.7) | 3.9 (0.2) | 2.0 (0.1) | |||
EoL | FP | Test | 98.4 (6.7) | 56.6 (4.6) | 39.6 (3.8) | 3.9 (0.2) | 1.9 (0.0) | |
Ref | 101.0 (6.7) | 55.2 (4.3) | 39.7 (3.4) | 3.7 (0.2) | 2.0 (0.0) | |||
Sal | Test | 102.3 (3.8) | 9.1 (0.7) | 6.2 (0.6) | 4.1 (0.2) | 1.9 (0.0) | ||
Ref | 102.3 (7.2) | 9.6 (0.8) | 6.6 (0.7) | 4.0 (0.2) | 2.1 (0.1) | |||
60 | BoL | FP | Test | 101.2 (4.7) | 59.7 (4.5) | 47.1 (4.0) | 3.6 (0.1) | 1.9 (0.0) |
Ref | 100.7 (2.7) | 58.1 (3.0) | 49.2 (4.0) | 3.1 (0.2) | 2.0 (0.1) | |||
Sal | Test | 105.5 (3.7) | 9.5 (0.7) | 7.3 (0.5) | 3.7 (0.1) | 2.0 (0.0) | ||
Ref | 101.5 (2.8) | 9.9 (0.7) | 8.1 (0.7) | 3.3 (0.2) | 2.1 (0.0) | |||
EoL | FP | Test | 100.1 (3.7) | 62.9 (5.1) | 52.6 (5.3) | 3.3 (0.2) | 1.9 (0.1) | |
Ref | 103.3 (3.3) | 59.4 (3.2) | 49.3 (3.7) | 3.2 (0.2) | 2.0 (0.1) | |||
Sal | Test | 104.7 (3.4) | 10.0 (0.8) | 7.9 (0.7) | 3.5 (0.1) | 1.9 (0.0) | ||
Ref | 104.3 (3.7) | 10.2 (0.7) | 8.2 (0.7) | 3.4 (0.2) | 2.1 (0.0) | |||
90 | BoL | FP | Test | 100.2 (3.8) | 54.7 (4.2) | 47.5 (4.0) | 3.4 (0.2) | 2.0 (0.0) |
Ref | 99.2 (3.0) | 53.6 (4.5) | 48.1 (4.5) | 3.1 (0.1) | 2.1 (0.1) | |||
Sal | Test | 106.3 (3.2) | 8.7 (0.6) | 7.4 (0.5) | 3.7 (0.1) | 2.0 (0.0) | ||
Ref | 102.1 (3.0) | 9.2 (1.0) | 8.2 (0.9) | 3.3 (0.2) | 2.2 (0.1) | |||
EoL | FP | Test | 100.6 (3.1) | 59.6 (4.6) | 52.7 (4.5) | 3.2 (0.2) | 2.0 (0.0) | |
Ref | 102.8 (3.6) | 54.2 (3.4) | 48.2 (3.4) | 3.2 (0.1) | 2.1 (0.1) | |||
Sal | Test | 106.3 (2.6) | 9.4 (0.6) | 8.1 (0.6) | 3.4 (0.2) | 2.0 (0.0) | ||
Ref | 105.3 (3.7) | 9.3 (0.7) | 8.1 (0.7) | 3.4 (0.2) | 2.2 (0.1) |
Ref, reference; Sal, salmeterol; Test, Wixela Inhub.