Table 12.
Flow rate | Lifestage | Active | Product | MB (%), mean (SD) | ISM (μg), mean (SD) | FPM (μg), mean (SD) | MMAD (μm), mean (SD) | GSD (μm), mean (SD) |
---|---|---|---|---|---|---|---|---|
30 | BoL | FP | Test | 98.1 (3.5) | 101.0 (7.6) | 67.4 (6.7) | 4.1 (0.2) | 1.8 (0.0) |
Ref | 93.1 (23.0) | 99.8 (25.6) | 72.8 (18.9) | 3.7 (0.1) | 1.9 (0.0) | |||
Sal | Test | 102.0 (2.1) | 8.9 (0.5) | 5.7 (0.4) | 4.4 (0.1) | 1.8 (0.0) | ||
Ref | 94.5 (23.4) | 8.8 (2.3) | 6.2 (1.6) | 3.9 (0.2) | 1.9 (0.0) | |||
EoL | FP | Test | 99.0 (3.9) | 111.3 (10.3) | 78.6 (9.1) | 3.9 (0.1) | 1.8 (0.0) | |
Ref | 99.1 (11.7) | 107.4 (13.3) | 75.9 (10.1) | 3.9 (0.1) | 1.9 (0.0) | |||
Sal | Test | 103.4 (3.1) | 10.0 (0.7) | 6.8 (0.6) | 4.1 (0.1) | 1.8 (0.0) | ||
Ref | 100.4 (12.1) | 9.5 (1.2) | 6.5 (0.9) | 4.1 (0.1) | 1.9 (0.0) | |||
60 | BoL | FP | Test | 100.1 (3.6) | 118.8 (9.7) | 96.9 (10.4) | 3.4 (0.2) | 1.9 (0.1) |
Ref | 99.1 (2.0) | 117.2 (6.0) | 102.3 (7.2) | 3.0 (0.2) | 1.9 (0.1) | |||
Sal | Test | 104.1 (3.1) | 10.2 (0.6) | 8.0 (0.5) | 3.7 (0.1) | 1.9 (0.1) | ||
Ref | 99.8 (2.4) | 10.1 (0.5) | 8.4 (0.6) | 3.2 (0.2) | 2.0 (0.1) | |||
EoL | FP | Test | 99.6 (3.5) | 131.5 (11.3) | 112.6 (11.1) | 3.2 (0.1) | 1.8 (0.0) | |
Ref | 103.3 (3.3) | 121.8 (6.6) | 104.5 (8.0) | 3.1 (0.1) | 1.9 (0.1) | |||
Sal | Test | 104.4 (3.2) | 11.2 (0.7) | 9.2 (0.8) | 3.4 (0.1) | 1.8 (0.1) | ||
Ref | 104.7 (3.2) | 10.6 (0.6) | 8.6 (0.6) | 3.3 (0.1) | 2.0 (0.0) | |||
90 | BoL | FP | Test | 101.2 (3.3) | 124.0 (9.4) | 109.3 (8.8) | 3.2 (0.1) | 1.9 (0.0) |
Ref | 98.7 (2.0) | 117.9 (6.2) | 106.7 (6.2) | 2.9 (0.1) | 2.0 (0.0) | |||
Sal | Test | 104.7 (3.0) | 10.4 (0.6) | 8.9 (0.5) | 3.5 (0.1) | 1.9 (0.0) | ||
Ref | 99.3 (2.2) | 10.1 (0.6) | 9.0 (0.6) | 3.1 (0.1) | 2.0 (0.0) | |||
EoL | FP | Test | 101.2 (3.2) | 129.1 (10.1) | 114.4 (9.5) | 3.1 (0.1) | 1.9 (0.0) | |
Ref | 103.7 (3.9) | 124.1 (7.7) | 111.6 (7.4) | 3.0 (0.1) | 2.0 (0.0) | |||
Sal | Test | 104.7 (2.4) | 10.9 (0.6) | 9.4 (0.6) | 3.4 (0.1) | 1.9 (0.0) | ||
Ref | 104.2 (3.7) | 10.6 (0.6) | 9.4 (0.6) | 3.2 (0.1) | 2.0 (0.1) |
Ref, reference; Sal, salmeterol.