Table 2.
Association Between Maternal Prepregnancy Body Mass Index and Group B Streptococcus Colonization in Pregnancy (n = 115,070)
| Maternal prepregnancy BMI category (kg/m2) | Frequency of GBS colonization (row percentage) |
Unadjusted and adjusted estimatesa,b,c |
||
|---|---|---|---|---|
| Yes n = 23,625 n (%) | No n = 91,445 n (%) | Unadjusted odds ratio, OR (95% CI) | Adjusted odds ratio, AOR (95% CI) | |
| Normal weight or below (<25 kg/m2) | 13,543 (19.3) | 56,555 (80.6) | 1.00 (reference) | 1.00 (reference) |
| Overweight (25–29.9 kg/m2) | 5,353 (20.8) | 20,380 (79.2) | 1.09 (1.05–1.13) | 1.10 (1.06–1.14) |
| Obesity class I (30–34.9 kg/m2) | 2,596 (23.0) | 8,679 (76.9) | 1.24 (1.19–1.31) | 1.25 (1.19–1.32) |
| Obesity class II (35–39.9 kg/m2) | 1,270 (26.1) | 3,580 (73.8) | 1.48 (1.38–1.58) | 1.47 (1.38–1.58) |
| Obesity class III (≥40 kg/m2) | 863 (27.7) | 2,251 (72.2) | 1.60 (1.47–1.73) | 1.59 (1.46–1.72) |
a
Logistic regression with generalized estimating equations modeled the associations accounting for within-woman correlations (i.e., participants with multiple deliveries during the study period).
b
Adjusted models included: maternal age, parity, race, pregestational diabetes, insurance status, study site/region, and delivery year.
c
Data imputation was performed for the following covariates: age, race, insurance status, and delivery year.
BMI, body mass index; CI, confidence interval.