Table 1.
Administered Doses of Survanta and Aerosol Excipient Enhanced Growth Survanta
| Administration method | Dose of Survanta®or EEG Survanta | Aerosol emitted dose (%) | PL dose (mg) |
|---|---|---|---|
| Instillation | 0.75 (0.1) mL | NA | 18.6 (2.6) |
| Instillation | 1.36 (0.1) mL | NA | 34.0 (2.0) |
| Aerosol | 3.05 (0.03) mg | 73.7 (9.3) | 0.61 (0.08) |
| Aerosol | 5.02 (0.04) mg | 71.4 (6.6) | 0.97 (0.09) |
| Aerosol | 10.04 (0.04) mg | 63.6 (6.3) | 1.73 (0.17) |
| Aerosol | 20.08 mga | NA | 3.46a |
Liquid and EEG Survanta aerosol doses are represented as mean and standard deviation (in parentheses) of loaded doses where applicable with their corresponding delivery percentage and PL content, n = 5–7.
a
Calculated as 2 × 10.04 mg dose.
EEG, excipient enhanced growth; PL, phospholipid.