Table 2.
Visual Characteristics of Study Population
| Participants | Participants | ||
|---|---|---|---|
| with Vision | with Normal | ||
| Impairment (n = 62) | Vision (n = 40) | P (df)a | |
| Ocular diagnosis, n (%) | <0.001* | ||
| Achromatopsia, cone dystrophy | 7 (11.3) | 0 (0.0) | |
| Albinism, congenital nystagmus | 27 (43.6) | 0 (0.0) | |
| Optic atrophy | 8 (12.9) | 0 (0.0) | |
| Optic nerve hypoplasia | 4 (6.5) | 0 (0.0) | |
| Other | 6 (9.7) | 0 (0.0) | |
| Retinal degeneration/dystrophy | 8 (12.9) | 0 (0.0) | |
| Retinopathy of prematurity | 2 (3.2) | 0 (0.0) | |
| None (control) | 0 (0.0) | 40 (100.0) | |
| Best-corrected distance visual acuity (logMAR), mean (SD) | |||
| OD | 0.7 (0.2) | –0.08 (0.05) | <0.001* (67.8) |
| OS | 0.7 (0.3) | –0.09 (0.05) | <0.001* (64.0) |
| OU | 0.6 (0.2) | –0.12 (0.04) | <0.001* (67.0) |
| Reading acuity OU (logMAR), mean (SD) | 0.57 (0.23) | –0.15 (0.10) | <0.001* (67.0) |
| Nystagmus, n (%) | 41 (67.2) | 0 (0.00) | <0.001* (1) |
| Mars Contrast Sensitivity, mean (SD) | 1.6 (0.2) | 1.8 (0.05) | <0.001* (70.8) |
Comparisons used t-tests for continuous variables (pooled for equal variances and Satterthwaite for unequal variances) and χ2 tests for categorical variables or Fisher's exact test if >20% of cell frequencies were <5.
a
If degrees of freedom are not indicated, a Fisher's exact test was used.
*