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. Author manuscript; available in PMC: 2020 Dec 23.

Published in final edited form as: Adv Pediatr Res. 2019 Jan 12;5(3):23. doi: 10.24105/apr.2019.5.23

Figure 1. — A) Abbreviated case-definitions for the fetal alcohol spectrum disorder (FASD) 4-Digit Code [2]. The 4-Digit Code 3434 is one of 12 4-Digit Codes that fall under the diagnostic category FAS. B) The Rank 4 FAS facial phenotype requires 3 features: 1) palpebral fissure lengths 2 or more standard deviations below the mean; 2) a smooth philtrum (Rank 4 or 5 on the University of Washington Lip-Philtrum Guide); and 3) a thin upper lip (Rank 4 or 5 on the University of Washington Lip-Philtrum Guide). C and D) The 4-Digit Code produces four diagnostic subgroups under the umbrella of FASD: FAS (Diagnostic Categories A, B), PFAS (Diagnostic Category C), SE/AE (Diagnostic Categories E, F), and ND/AE (Diagnostic Categories G, H). Abbreviations: CNS: central nervous system; H: height percentile; W: weight percentile.

Figure 1. — A) Abbreviated case-definitions for the fetal alcohol spectrum disorder (FASD) 4-Digit Code [2]. The 4-Digit Code 3434 is one of 12 4-Digit Codes that fall under the diagnostic category FAS. B) The Rank 4 FAS facial phenotype requires 3 features: 1) palpebral fissure lengths 2 or more standard deviations below the mean; 2) a smooth philtrum (Rank 4 or 5 on the University of Washington Lip-Philtrum Guide); and 3) a thin upper lip (Rank 4 or 5 on the University of Washington Lip-Philtrum Guide). C and D) The 4-Digit Code produces four diagnostic subgroups under the umbrella of FASD: FAS (Diagnostic Categories A, B), PFAS (Diagnostic Category C), SE/AE (Diagnostic Categories E, F), and ND/AE (Diagnostic Categories G, H). Abbreviations: CNS: central nervous system; H: height percentile; W: weight percentile.