Table 2.

Relationships (Odds Ratio and 95% Confidence Intervals) of Renal Dysfunction to Therapeutic Dose of Acetaminophen and/or Light/Moderate Amount of Alcohol Among Various Gender, Racial, and Age Groups (National Health and Nutrition Examination Survey 2003–2004)

Sociodemographic characteristics	Crude		Adjusteda
	Self-report renal dysfunction	SCr ≥1.0 mg/dL	Self-report renal dysfunction	SCr ≥1.0 mg/dL
Gender
Female	1.90 (1.33–2.70)	4.20 (2.88–6.12)	1.87 (1.19–2.95)	0.85 (0.36–2.01)
Male	1.37 (0.92–2.05)	2.20 (1.63–2.97)	1.19 (0.46–3.08)	1.59 (0.96–2.64)
Race
White	1.63 (1.23–2.16)	1.90 (1.51–2.39)	1.87 (1.14–3.08)	0.80 (0.39–1.62)
Black	2.27 (1.45–3.54)	2.13 (1.29–3.53)	1.05 (0.22–5.08)	2.40 (0.79–7.32)
Hispanic	1.50 (0.71–3.16)	2.91 (1.23–6.93)	1.04 (0.23–4.75)	0.61 (0.06–6.17)
Other	0.84 (0.19–3.68)	5.82 (1.83–18.51)	3.63 (0.20–64.84)	22.26 (1.15–328.63)
Age (years)
<21	—	11.21 (4.74–26.52)	—	9.01 (1.88–43.13)
21–30	3.20 (0.68–15.10)	1.28 (0.28–5.78)	7.52 (2.00–28.29)	0.37 (0.04–3.21)
>+30 to <65	1.19 (0.84–1.69)	1.13 (0.81–1.57)	1.35 (0.88–2.07)	1.26 (0.80–1.98)
≥65	1.00 (0.69–1.45)	1.11 (0.83–1.49	1.01 (0.59–1.73)	1.40 (0.89–2.22)
Education
High school and below	1.49 (0.99–2.25)	1.43 (0.96–2.14)	0.90 (0.44–1.81)	0.70 (0.41–1.20)
High graduate and some college	1.68 (1.22–2.33)	1.60 (1.24–2.07)	1.87 (1.16–3.01)	1.78 (1.14–2.80)
College graduate	1.73 (0.99–3.02)	1.08 (0.65–1.80)	1.57 (0.62–3.95)	1.23 (0.44–3.41)
Household income
<25K	1.50 (0.94–2.40)	3.03 (2.14–4.29)	1.44 (0.74–2.81)	1.91 (1.00–3.65)
25 to <75K	1.37 (0.97–1.95)	2.19 (1.50–3.20)	1.25 (0.66–2.36)	1.50 (0.92–2.42)
≥75K	2.39 (1.27–4.50)	1.44 (0.90–2.32)	2.34 (0.99–5.53)	1.11 (0.45–2.76)
≥25K	1.65 (1.18–2.30)	1.95 (1.46–2.59)	1.49 (0.94–2.38)	1.33 (0.89–1.98)

eGFR (based on the 2009 Chronic Kidney Disease–Epidemiology Collaboration equation): Crude OR (95% CI)=3.22 (2.45–4.24); adjusted: 2.65 (1.72–4.09). This will go in results text.

^aAdjusted for hypertension, obesity, and diabetes.eGFR, estimated glomerular filtration rate.