Table 2.
Relationships (Odds Ratio and 95% Confidence Intervals) of Renal Dysfunction to Therapeutic Dose of Acetaminophen and/or Light/Moderate Amount of Alcohol Among Various Gender, Racial, and Age Groups (National Health and Nutrition Examination Survey 2003–2004)
| Sociodemographic characteristics | Crude |
Adjusteda |
||
|---|---|---|---|---|
| Self-report renal dysfunction | SCr ≥1.0 mg/dL | Self-report renal dysfunction | SCr ≥1.0 mg/dL | |
| Gender | ||||
| Female | 1.90 (1.33–2.70) | 4.20 (2.88–6.12) | 1.87 (1.19–2.95) | 0.85 (0.36–2.01) |
| Male | 1.37 (0.92–2.05) | 2.20 (1.63–2.97) | 1.19 (0.46–3.08) | 1.59 (0.96–2.64) |
| Race | ||||
| White | 1.63 (1.23–2.16) | 1.90 (1.51–2.39) | 1.87 (1.14–3.08) | 0.80 (0.39–1.62) |
| Black | 2.27 (1.45–3.54) | 2.13 (1.29–3.53) | 1.05 (0.22–5.08) | 2.40 (0.79–7.32) |
| Hispanic | 1.50 (0.71–3.16) | 2.91 (1.23–6.93) | 1.04 (0.23–4.75) | 0.61 (0.06–6.17) |
| Other | 0.84 (0.19–3.68) | 5.82 (1.83–18.51) | 3.63 (0.20–64.84) | 22.26 (1.15–328.63) |
| Age (years) | ||||
| <21 | — | 11.21 (4.74–26.52) | — | 9.01 (1.88–43.13) |
| 21–30 | 3.20 (0.68–15.10) | 1.28 (0.28–5.78) | 7.52 (2.00–28.29) | 0.37 (0.04–3.21) |
| >+30 to <65 | 1.19 (0.84–1.69) | 1.13 (0.81–1.57) | 1.35 (0.88–2.07) | 1.26 (0.80–1.98) |
| ≥65 | 1.00 (0.69–1.45) | 1.11 (0.83–1.49 | 1.01 (0.59–1.73) | 1.40 (0.89–2.22) |
| Education | ||||
| High school and below | 1.49 (0.99–2.25) | 1.43 (0.96–2.14) | 0.90 (0.44–1.81) | 0.70 (0.41–1.20) |
| High graduate and some college | 1.68 (1.22–2.33) | 1.60 (1.24–2.07) | 1.87 (1.16–3.01) | 1.78 (1.14–2.80) |
| College graduate | 1.73 (0.99–3.02) | 1.08 (0.65–1.80) | 1.57 (0.62–3.95) | 1.23 (0.44–3.41) |
| Household income | ||||
| <25K | 1.50 (0.94–2.40) | 3.03 (2.14–4.29) | 1.44 (0.74–2.81) | 1.91 (1.00–3.65) |
| 25 to <75K | 1.37 (0.97–1.95) | 2.19 (1.50–3.20) | 1.25 (0.66–2.36) | 1.50 (0.92–2.42) |
| ≥75K | 2.39 (1.27–4.50) | 1.44 (0.90–2.32) | 2.34 (0.99–5.53) | 1.11 (0.45–2.76) |
| ≥25K | 1.65 (1.18–2.30) | 1.95 (1.46–2.59) | 1.49 (0.94–2.38) | 1.33 (0.89–1.98) |
eGFR (based on the 2009 Chronic Kidney Disease–Epidemiology Collaboration equation): Crude OR (95% CI)=3.22 (2.45–4.24); adjusted: 2.65 (1.72–4.09). This will go in results text.
a
Adjusted for hypertension, obesity, and diabetes.eGFR, estimated glomerular filtration rate.