Table 2.
Recipients | Treatment | Animal ID | Pregnancy outcome | Calving data | Sex of offspring |
---|---|---|---|---|---|
1 | bPRNP | 752 | Pregnant | Twins (1 normal +1 stillborn) | Male* |
FemaleSB | |||||
2 | bPRNP | 769 | Pregnant | 1 calf | Male |
3 | bPRNP | 772 | Nonpregnant | ||
4 | bPRNP | 774 | Pregnant | 1 calf | Female |
5 | bPRNP | 786 | Pregnant | 1 calf | Male |
6 | bPRNP | 789 | Pregnant | 2 calves (1 euthanized) | Male |
7 | bPRNP | 804 | Nonpregnant | ||
8 | bPRNP | 819 | Nonpregnant | ||
9 | bPRNP | 827 | Pregnant | 1 calf | Male |
10 | Control | 806 | Nonpregnant | ||
11 | Control | 809 | Pregnant | 1 calf | Male |
12 | Control | 829 | Nonpregnant | ||
Total live calves at birth | 6 edited calves; | ||||
1 wildtype control calf |
Calf 752 male died two days after birth.
bPRNP, bovine prion protein.