Appendix C.

Adjusted Linear Regression Models to Provide More Information on Interaction Findings

	<6 Months of MAUD				>6 Months of MAUD
	Detectable VL		Undetectable VL		Detectable VL		Undetectable VL
Treatment Intensity	Coef	95% CI	Coef	95% CI	Coef	95% CI	Coef	95% CI
VACS Index Score 2.0 change	NA		n=2186		NA		n=274
1 Day Only (referent group)
Minimal	NA		0.21	−0.62–1.04	NA		−3.75	−6.24–1.33
Moderate			0.98	−0.19–2.16			−1.87	−5.05–1.10
Intensive			−0.19	−2.62–2.24			−0.33	−6.16–5.51
			p=.4				p=.02
ARV Adherence change**	n=1488		n=2494		n=161		n=333
1 Day Only (referent group)
Minimal	0.01	−0.02–0.03	−0.00	−0.01–0.01	0.04	−0.02–0.10	−0.00	−0.04–0.03
Moderate	0.02	−0.01–0.05	−0.00	−0.02–0.01	0.06	−0.00–0.13	−0.02	−0.06–0.02
Intensive	0.10	0.04–0.16	0.09	0.05–0.13	0.04	−0.06–0.15	0.03	−0.05–0.11
	p=.007		p<.001		p=.2		p=.6

^*Models are adjusted for age and race/ethnicity, gender, smoking, HCV drug diagnosis, severe mental illness (SMI), and AUDIT-C. VACS Index change model is also adjusted for number of days between pre and post values for VACS Index change.