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. 2020 Dec 23;15(12):e0243995. doi: 10.1371/journal.pone.0243995

Table 1. Demographics and comorbidities of patients who underwent colorectal cancer resections at The Prince Charles Hospital between 2010–2018.

Feature Number of nil/ low grade complications Number of high grade complications Total P-value
(% of nil/low grade complications) (% of high grade complications)
Patients 448 (84) 85 (16) 533
Gender 
    • Male 215 (48) 52 (61) 267 0.03
    • Female 233 (52) 33 (39) 266
Median age 70 74 67 0.01
    • (range) 17–96 31–90 17–96
Median BMI 27 28 27
    • (range) 15–59 15–40
    • <20 31 (7) 6 (7) 37 0.24
    • 20–24.9 119 (27) 21 (25) 140
    • 25–29.9 171 (38) 27 (32) 198
    • 30–39.9 110 (25) 30 (35) 140
    • >40 17 (4) 1 (1) 18
Median ASA 3 3
    • Grade I 37 (8) 4 (5) 41 0.016
    • Grade II 165 (37) 19 (22) 185
    • Grade III 211 (47) 49 (58) 259
    • Grade IV 34 (8) 13 (15) 47
    • Grade V 1 (0) 0 (0) 1
Cardiac 
    • Ischaemic Heart Disease 74 (17) 24 (28) 98 0.014
    • Coronary Artery Bypass Graft 29 (7) 11 (13) 40 0.045
    • Percutaneous Coronary Intervention 26 (6) 7 (8) 33 0.46
    • Pacemaker insertion 8 (2) 1 (1) 9 0.69
    • Cardiac valve replacement 17 (4) 3 (4) 20 1.0
    • Heart failure (all types) 14 (3) 8 (9) 22 0.014
    • Cardiomyopathy 10 (2) 8 (9) 18 <0.001
    • AICD insertion 6 (1) 1 (1) 7 0.90
    • Hypertension 224 (50) 42 (50) 266 1.0
    • Pulmonary hypertension 5 (1) 1 (1) 6 0.903
    • Atrial fibrillation 48 (10) 23 (27) 71 <0.001
Respiratory
    • Asthma 49 (11) 9 (11) 58 1.0
    • COPD 44 (9) 18 (21) 62 0.005
    • Bronchiectasis 6 (1) 0 (0) 6 -
    • Cystic fibrosis 1 (0) 0 (0) 1 -
    • Obstructive sleep apnoea 28 (6) 6 (7) 34 0.81
Metabolic
    • Type I Diabetes 2 (0) 0 (0) 2 -
    • Type II Diabetes 84 (19) 12 (14) 96 0.36
    • Hyperlipidaemia 131 (29) 27 (32) 158 0.70
Previous cancer 59 (13) 17 (20) 76 0.098
Autoimmune
    • Rheumatoid arthritis 3 (1) 0 (0) 3 0.80
    • Psoraisis 8 (2) 1 (1) 9
    • Polymyalgia rheumatica 6 (1) 0 (0) 6
    • SLE 1 (0) 0 (0) 1
Pre-operative renal function
    • eGFR >90 260 (58) 44 (52) 304 0.60
    • eGFR 60–89 133 (30) 25 (30) 158
    • eGFR 45–59 38 (9) 11 (13) 49
    • eGFR 30–44 16 (4) 3 (4) 19
    • eGFR 15–29 2 (1) 1 (1) 3
    • eGFR < 15 0 (0) 0 (0) 0
Current Smoker (within 12 months) 63 (14) 13 (15) 76

BMI, Body Mass Index; ASA, American Society of Anaesthesiologists Physical Status Classification; AICD, Automatic Implantable Cardioverter Defibrillator; COPD, Chronic Obstructive Pulmonary Disease; SLE, Systemic lupus erythematosus.