Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 23;9:e59545. doi: 10.7554/eLife.59545

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020, Uchigashima et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

PMC Copyright notice

Figure 9. — (A–D) Effect of pre- and postsynaptic overexpression (OE) of βNrxn3(±AS4) and Nlgn3Δ, respectively, on unitary inhibitory synaptic transmission in organotypic slice cultures prepared from NrxnTKO/VGT3/RFP mice. (E–H) Effect of pre- and postsynaptic OE of αNrxn3(±AS4) and Nlgn3Δ, respectively, on unitary inhibitory synaptic transmission. (A and E) Averaged sample unitary inhibitory postsynaptic current (uIPSC) traces. Summary of uIPSC amplitude (B and F), paired-pulse ratio (C and G), and connectivity (D and H). Numbers of cell pairs: βNrxn3+AS4, βNrxn3-AS4, αNrxn3+AS4, and αNrxn3-AS4 at VGT3+ synapses (eight pairs/three mice, 9/3, 5/3, and 11/3). The number of tested slice cultures is the same as that of cell pairs. Mann–Whitney U-test.