Key resources table.

Reagent type (species) or resource	Designation	Source or reference	Identifiers	Additional information
Strain, strain background (Mus musculus)	B6;129S6-Gt(ROSA)26Sortm2(CAG-NuTRAP)Evdr/J	Cell Rep. 2017 Jan 24; 18(4): 1048–1061.	NuTRAP	https://www.jax.org/strain/029899
Strain, strain background (Mus musculus)	B6;129-Tg(Cdh5-cre)1Spe/J	JAX strain 017968	Cdh5-Cre, VE-Cadherin-CRE
Antibody	Pecam1 antibody; Rat monclonal	BD Pharmigen	Cat# 558736	(1:500)
Antibody	Pcm1; Rabbit polyclonal	Sigma	Cat# HPA023370	(1:250)
Software, algorithm	fastp	Chen et al., 2018
Software, algorithm	Bowtie2	Langmead and Salzberg, 2012
Software, algorithm	Genrich	https://github.com/jsh58/Genrich
Software, algorithm	Picard Tools	http://broadinstitute.github.io/picard/
Software, algorithm	samtools	Li et al., 2009
Software, algorithm	STAR	Dobin, 2013
Software, algorithm	Seurat	Stuart et al., 2019
Software, algorithm	R	https://www.r-project.org/
Software, algorithm	DiffBind	Ross-Innes et al., 2012
Software, algorithm	Deeptools	Ramírez et al., 2016
Software, algorithm	Homer	Heinz et al., 2010
Software, algorithm	Velocyto	La Manno et al., 2018
Other	DAPI stain	Molecular Probes		(1:1000)
Other	RNAscope Probe- Mm-Tnnt2-C3	ACD Bio	Cat# 418681-C3
Other	RNAscope Probe- Mm-Cdh5-C2	ACDBio	Cat# 312531-C2
Commercial assay or kit	RNAscope Multiplex Fluorescent v2 Assay	ACD Bio	Cat# 323136
Commercial assay or kit	Illumina Tagment DNA Enzyme and Buffer	Illumina	Cat#:20034197	1.25 uL of enzyme used per 50,000 nuclei for transposition