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. 2020 Oct 29;9:e62071. doi: 10.7554/eLife.62071

Figure 4. Vasodilation tracks transitions between arousal states.

(A) Schematic of each data type. (B) Transition from periods classified as rfc-Awake into periods classified as rfc-NREM. Top: Average change in total hemoglobin ∆[HbT] within the ROI and normalized change in EMG power. Shaded regions indicate ± 1 standard deviation (n = 14 mice, 28 hemispheres). (C) Transition from periods classified as rfc-NREM into periods classified as rfc-Awake. (D) Transition from periods classified as rfc-NREM into periods classified as rfc-REM. (E) Transitions from periods classified as rfc-REM into periods classified as rfc-Awake. (F) Mean arteriole diameter during the transition of NREM into REM (n = 5 mice, 8 arterioles). (G) Mean arteriole diameter during the transition from REM into Awake (n = 5 mice, 8 arterioles). Note that the EMG scales are different across conditions.

Figure 4.

Figure 4—figure supplement 1. Transitional changes in hemodynamics are consistent across each day.

Figure 4—figure supplement 1.

Average change in total hemoglobin ∆[HbT] for different days for various behavioral state transitions. Each colored line indicates a unique day of imaging (n = 14 mice). (A) Transition from rfc-Awake to rfc-NREM. (B) Transition from rfc-NREM to rfc-Awake. (C) Transition from rfc-NREM to rfc-REM. (D) Transitions from rfc-REM to rfc-Awake.