(a) The schematic illustration of basic principles of micromilling technology. Reproduced with permission from Guckenberger et al., Lab Chip 15, 2364–2378 (2015).48 Copyright 2015 Royal Society of Chemistry. (b) The schematic illustration of microchannel built with light-directed LEGO-like 3D-printed building block. Reproduced with permission from Valentin et al., Polym. Chem. 10, 2015–2028 (2019).49 Copyright 2019 Royal Society of Chemistry. (c) Schematic diagram and experimental images of a 3D PDMS microchannel fabricated by PDMS micromolding. Reproduced with permission from Jeong et al., Lab Chip 15, 4387–4392 (2015).50 Copyright 2015 Royal Society of Chemistry.