Table 1. VTE risk factor category descriptions and 1- and 5-year recurrence rates following discontinuation of anticoagulation therapy.

Risk factor category	1-year VTE recurrence rate 5 9	5-year VTE recurrence rate 2 57
Major transient	1%	3%
Major persistent	15%	NC a
Minor transient	4–6%	15%
Minor persistent	11%	∼30% b
Unprovoked	8–10%	30%

Abbreviations: NC, not calculable; VTE, venous thromboembolism.

^aUnable to calculate due to high mortality.

^b Based on the assumption described by Kearon et al in 2010 that the risk of recurrence after stopping anticoagulant therapy conforms to a negatively accelerating curve, and that the cumulative risk of recurrence after 5 years of follow-up is about three times the risk after the first year. ⁵⁷