TABLE 5.

Transplanted photoreceptors.

Source	Cell type	Description	Format	Model	Cell survival
E12.5-P28 days mice [1]	photoreceptors	Cells integrated well in the host retina and expressed equal markers	dissociated cells	mouse	2 w
hiPSCs [2]	photoreceptors	Photoreceptors survived and matured in the host eye	injected in clusters	rat	10 w
P4 mice/hiPSCs [3]	photoreceptors	Blind mice recovered visual function/mice showed signs of retinal repair	cell suspension	mouse	4 w
P4-8 mice [4]	Rod precursors	Rod precursors stablished synaptic connection with cells in retina of Gnat12/2 mice and were light-responsive	dissociated cells	mouse	6 w
P6-8 mice [5]	photoreceptors	Prph2+/Δ307 model showed higher integration of rods	cell suspension	mouse	4 w
P8 rat [6]	photoreceptors	Transplantation reduced cone loss 6 months after surgery	sheet	rat	24 w
Adult rats [7]	Full-thickness retina with attached RPE	well-preserved host photoreceptor layer and RPE integrated well	graft	rat	–

E, embryonic day; P, postnatal day; Gnat12/2 mice, a model of congenital stationary night blindness; hiPSCs, human induced pluripotent stem cells; Prph2^+/Δ307, model of retinitis pigmentosa. [1] (Gust and Reh, 2011); [2] (Gagliardi et al., 2018); [3] (Garita-Hernandez et al., 2019); [4] (Pearson et al., 2012); [5] (Barber et al., 2013); [6] (Yang et al., 2010); [7] (Lorach et al., 2019).